ACE2 and infection: Unlike a previous report that showed that some bat SARS-CoV–related viruses could use human and civet ACE2 and R. sinicus ACE2 as entry receptors (5,13,14), VSV-Rc-o319 was found to use only homologous Rc-ACE2, which arguably suggests that Rc-o319 and its related viruses might not jump the species barrier easily and cause infection.