The c.2207_2212delinsTAGATTC variant is the predominant pathogenic BLM variant identified in Ashkenazi Jews, a 6-bp deletion/7-bp insertion in exon 10 of BLM, often (for brevity) designated blmAsh, which has recently been described in a BS patient with nasopharyngeal carcinoma later in life [7]. This evidence concerns the gene BLM and nasopharyngeal carcinoma.