PDE10A is highly expressed in the GABAergic neurons of the olfactory tubercle and the striatum (MacMullen et al. 2017), is dysregulated in an animal model of postpartum depression (Yun et al. 2019), and has been genetically associated with bipolar disorder, hypo- and hyperthyroidism, and blood pressure (GWAS Catalog 2020). The gene discussed is PDE10A; the disease is bipolar disorder.