PTX3 and hepatocellular carcinoma: According to underlying liver disease, patients with chronic hepatitis and HCC (n = 23) had significantly higher PTX3 levels than patients with chronic hepatitis without HCC (n = 159) [13.3 (6.8–38.8) ng/mL vs. 3.7 (0.089–22.37) ng/mL, P < 0.001, Figure S2A].