In 203 lung cancer tissue samples, we detected a total of 313 EGFR GAs: 253 Substitution/Indels (including 250 Substitutions/Shortindels and 3 LongIndels, with 5 SNVs were belonging to germline mutation), 58 gene amplifications, and 2 fusions. The gene discussed is EGFR; the disease is lung cancer.