As presented in Tables 1 and 2, ZNF300 methylation tended to correlate with U2AF1 and SRSF2 mutations in MDS (P = 0.066 and 0.090, respectively), whereas its hypermethylation was associated with lower platelets and higher proportion of male patients/CEBPA mutations in AML (P = 0.002, 0.032, and 0.066, respectively). This evidence concerns the gene U2AF1 and myelodysplastic syndrome.