Next, Kaplan–Meier analyses showed that ZNF300 hypermethylated cases exhibited shorter OS and LFS time compared with ZNF300 non-hypermethylated cases in both non-M3 AML (P = 0.039 and 0.054, respectively) and CN-AML (P = 0.005 and 0.035, respectively) (Fig. 7e). The gene discussed is ZNF300; the disease is acute myeloid leukemia.