Analysis using the GEPIA dataset indicates that the YAP1 levels were positively correlated with TEAD1 in colon cancer, rectal cancer and CRC (Fig. S3A, Supporting Information), and surprisingly, the YAP1 and TEAD1 levels were both positively correlated with HIF1A (Fig. S3B, Supporting Information) or LDHA (Fig. S3C, Supporting Information). The gene discussed is TEAD1; the disease is rectal cancer.