LATS2 and esophageal squamous cell carcinoma: For example, it has been demonstrated that miR-135b regulates the Hippo pathway to promote lung cancer metastasis [26], and miR-31 inhibits the expression of LATS2 via the Hippo pathway and promotes epithelial-mesenchymal transition in esophageal squamous cell carcinoma (ESCC) [27].