ICB alone (Figure 2d) had modest effect on tumor growth that attained statistical significance (p = 0.033), with 3 doses of 250 μg anti-PD1 mAb on days 11, 14, and 17 showing a varied response, from complete cure to no effect when compared to unlabeled h8C3 (Figure 2a,d). This evidence concerns the gene PDCD1 and neoplasm.