Secondly, 1 inhibited in a good manner PDGFRs (especially PDGFR-β) and the mutations that occur in the exon 11 of the KIT gene, which encodes the juxta-membrane domain (V559D and L576P) (Table S3) involved, for example, in gastrointestinal stromal tumors [35]. The gene discussed is KIT; the disease is gastrointestinal stromal tumor.