DICER1 and thyroid tumor: Another study linked hotspot DICER1 mutations to pediatric PTC (c.5125G>A p.D1709N, c.5428G>T p.D1801Y, c.5438A>G p.E1813G, c.5439G>C p.E1813D) with increased incidence in the patients that do not harbor MAPK classic alterations [80], suggesting a role for DICER1 mutation detection in thyroid tumors.