TNF and cancer: Chronic gastric inflammation caused by the products secreted by H. pylori, which stimulates transcription and synthesis of inflammatory cytokines, especially interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) [4], is considered to play an important role in the development and promotion of gastric cancer, and other organs may see an increased risk of cancer under such inflammatory conditions [5].