Furthermore, Blumenthal et al. showed that anti-CEACAM6/CEACAM5 mAb fragments targeting the N and A1B1 domains of these antigens lead to block migration, endothelial cells adhesion and increased survival of mice with intrapulmonary micrometastases of human colon cancer [39]. The gene discussed is CEACAM6; the disease is malignant colon neoplasm.