Our in vitro experimental data demonstrated that HT1376 bladder cancer cells are highly resistant to FL118 treatment, while UMUC-3 bladder cancer cells are highly sensitive to FL118 treatment in terms of (1) cell growth/viability inhibition (Figure 1, Figure S1), (2) apoptosis induction (Figure 2, Figure S2), (3) anti-apoptotic protein inhibition (Figure 3, Figure S3), (4) the role of Kras status (Figure 6, Figure S6) and (5) ROS production (Figure 7). The gene discussed is KRAS; the disease is urinary bladder carcinoma.