ERBB2 and asthma: The precise mechanism of dysregulated ErbB2 expression in asthmatic airway epithelial cells is not well known, but the ERBB2 gene locus of 17q12-21 (between 35.0 and 35.5 Mb) which is known as the asthma susceptibly gene locus including ORMDL3/GSDMB, IKZF3 is a possible explanation for impaired expression among asthmatic subjects [53,54,55,56].