AHR and asthma: Another possible mechanism by which biseugenol shows anti-inflammatory effects could be through aryl hydrocarbon receptor binding, a ligand-activated transcription factor that belongs to the basic region-helix-loop-helix (bHLH) superfamily, that is linked to the upregulation of IL-22 [24], IL-25, IL-33, TSLP [25], and ROS production [26] in asthma.