Furthermore, neck circumference is closely related to glucose and lipid metabolism disorders, insulin resistance, etc, and is related to various components of metabolic syndrome.[27,28] Previous study[29] has included 3037 Caucasians aged 40 to 60 years old, the results have suggested that neck circumference is associated with blood pressure, blood glucose, lipids, and insulin level. The gene discussed is INS; the disease is Disorder of lipid metabolism.