SLC5A5 and neoplasm: Recently, a particular cellular metabolite (uridine diphosphate N-acetylglucosamine ) was even shown to directly control endocytic traffic proteins by regulating glycosylation [78], Of interest, we found levels of this metabolite to be markedly increased in quiescent cells, suggesting that quiescence could induce NIS endocytosis and reduce tumor cell uptake ability.