At the biennial meeting of the International Conference on Malignant Lymphoma (ICML) in Lugano, Switzerland (2017): Phase II Tazemetostat Trial (EPZ-6438) demonstrated an objective response rate of 29% in DLBCL with EZH2 mutation and 15% in DLBCL with wild-type EZH2 [222]. The gene discussed is EZH2; the disease is diffuse large B-cell lymphoma.