FDA has been approved CAR-T therapy (Clinical trials of chimeric genetically modified T cells for CD19 by Kite Pharma) for diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma (transformed follicular lymphoma, or TFL), not otherwise specified. The gene discussed is CD19; the disease is diffuse large B-cell lymphoma.