NFATC1 and infection: Without ionomycin treatment, 88% of GFP-NFATC1 was localized in the cytosol of VZV infected cells, while ionomycin treatment triggered a dramatic translocation of 94% of GFP-NFATC1 into the nuclei of infected cells (Fig 5B), indicating that calcineurin phosphatase was retained during infection.