ACE2 and cancer: Because of surgery, the lack of a functional nose able to filter, humidify, and warm inhaled air, with a possible direct inhalation of infected droplet and aerosol into the lungs, together with a higher ACE2 expression on epithelial lower respiratory cells, due to former cigarette-smoking exposure, might justify the higher risk of SARS-CoV-2 infection with an early severe pneumonia documented by us and others in this specific cancer population.