In this study, we explored the expression patterns and prognosis values of 25 p‐EMT‐related genes and identified five key p‐EMT‐related genes associated with prognosis of HCC, including two common p‐EMT‐related genes P4HA2, ITGA5 and three variable p‐EMT‐related genes MMP9, MT1X, SPP1. This evidence concerns the gene MMP9 and hepatocellular carcinoma.