Second, researchers can further elucidate the molecular details of miR‐27a‐5p's mechanism of action to determine how the miR‐27a‐5p/Egr3 axis affects CF‐mediated myocardial fibrosis and the significance of the Tgf‐β cascade in this biological process. The gene discussed is EGR3; the disease is Myocardial fibrosis.