These findings suggested that FoxM1 was significantly overexpressed in esophageal carcinoma (ESCA), stomach adenocarcinoma (STAD), colon adenocarcinoma (COAD), and rectal adenocarcinoma (READ) tumor tissues compared to paired normal tissues (P < 0.05) (Fig. 1A). Here, FOXM1 is linked to rectum adenocarcinoma.