A number of gene nodes linked to drug resistance in other cancer types (including CAT, TRIM59, ANXA2, ADM, AJUBA, HSPA1A/1B, LAMC2, TRIM14, KRT8, KRT18, KRT9, CLDN1, and SMARCA2) were also down-regulated in PARPis-sensitive AsPCs (see Additional file 7). Here, TRIM59 is linked to cancer.