Thus, C-MET, CDKN2A, P-glyc (ABCB1) and N-cadherin displayed significantly lower protein expression levels in HGSOC tumors corresponding to PARPis-sensitive AsPCs (Fig. 5a–d), while FANCF and SPRY2 showed stronger expression in the PARPis-sensitive AsPCs-matched tumor samples (Fig. 5e–f). This evidence concerns the gene SPRY2 and neoplasm.