rs2294008 may also affect bladder cancer through a pathway that involves LYNX1 and SLURP1. Recent research suggests that PSCA, LYNX1, and SLURP1 bind to [31, 32] and modulate [27] the α7 subunit of nicotinic acetylcholine receptors [33, 34]. The gene discussed is LYNX1; the disease is urinary bladder carcinoma.