There was a significant correlation between pCR and lymphovascular invasion (P = 0.017), ER (P = 0.028), PR (P = 0.006), molecular subtype, Ki67 (P = 0.006), NCT regimen (P = 0.025) and anemia (hemoglobin≤120 g/L) (P = 0.033). This evidence concerns the gene ESR1 and anemia.