Apart from all of the other aminochalcones discussed earlier, Liu et al. [66] also synthesized some 4′-aminochalcones (Figure 62) which were tested for their ability to selectively inhibit P-glycoprotein (Pgp; ABCB1) and breast cancer-resistant protein (BCRP; ABCG2). The gene discussed is ABCG2; the disease is cancer.