These findings are summarized in Figure 5, and our companion review piece provides additional information on the role of BLK, HCK, FRK, ABL2, DDR1, LYN, EPHA8, FYN, LCK, and TEC kinases in PDAC and pancreatic cancer desmoplasia [107]. This evidence concerns the gene EPHA8 and familial pancreatic carcinoma.