STAT3 and gastric carcinoma: There is also evidence that Fascin is a putative target of β-catenin–T-cell factor (TCF) signaling in colon and gastric carcinomas [95,96], Transforming growth factor beta (TGFβ) signaling in breast carcinomas [97,98] and STAT3/ Nuclear factor kappa B (NF-kB) signaling in breast and gastric carcinomas [99,100].