LDLR and colorectal cancer: Very recently, Mohammad-Sadeghipour, Mahmoodi, Karimabad, and Mirzaei [47] found that a hydroalcoholic extract obtained from fenugreek also upregulated the expression of LDLR in SW480 colorectal cancer cell lines, although the expression of FASN was downregulated by the extract, as opposed to our findings.