However, in renal cell carcinoma, breast cancer, lung adenocarcinoma, and colorectal cancer, miR‐362‐3p are all under‐expressed, and inhibit various biological behaviors of cells by regulating hERG, E2F1, USF2, and PTPN.8, 9, 23, 24, 25. The gene discussed is E2F1; the disease is hereditary clear cell renal cell carcinoma.