To investigate the function of xCT in the resistance of tumours to chemotherapy, several studies have employed SSZ as an inhibitor of xCT (Gout et al., 2001; Ishimoto et al., 2011; Ma et al., 2015; Ogihara et al., 2019; Wada et al., 2018; Yoshikawa et al., 2013). Here, SLC7A11 is linked to neoplasm.