In HCC, previous studies found VEGFR and VEGF could be simultaneously overexpressed in several human HCC cell lines to promote cell proliferation and invasiveness and inhibit apoptosis, such as 7721, 7402, HepG2, MHCC‐97H and Huh7.31, 32, 33. The gene discussed is KDR; the disease is hepatocellular carcinoma.