Besides, a cohort study illustrates that in patients with RA, the prevalence of hypothyroidism and subclinical hypothyroidism are 12% and 11%, respectively; and RA patients with treated hypothyroidism/subclinical hypothyroidism have decreased quantitative insulin sensitivity check index (QUICKI) score and increased homeostasis model assessment for insulin resistance (HOMA‐IR) score (which indicate insulin resistance) compared to RA patients with adequate thyroid function.24 The gene discussed is INS; the disease is hypothyroidism.