VDR and osteoporosis: After a series of candidate gene studies, a number of “osteoporosis genes” (including, but not limited to, vitamin D receptor [VDR], collagen type 1 alpha 1 genes) have been identified.(9) However, these candidate gene studies were marred by conflicting findings, limited reproducibility, and possibly false‐positives,(10) which were perhaps based mainly on the lack of statistical power.(11)