This includes upregulation of emilin2a, which is known to block cancer cell proliferation;(29) and sfrp2, which controls normal osteoblast differentiation and exerts an antiapoptotic effect.(30, 31) Among downregulated genes, we identified gimap1‐like, which is essential for development of T and B lymphocytes; rad18, which is a key player in controlling DNA damage tolerance(32, 33); and ogdh, which is involved in glucose oxidation and cancer cell viability(34, 35) (Fig. 4D). The gene discussed is SFRP2; the disease is cancer.