PCSK9 and coronary artery disorder: Therefore, reducing lipid levels and recognizing who would benefit from a targeted reduction in lipid levels are cornerstones of decreasing mortality in CAD [2]. The efficacy and safety of lipid-lowering medications such as statins and proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9 inhibitors) have been thoroughly studied and proven beneficial in lowering lipid levels [5,6].