ACE and lip and oral cavity carcinoma: Therefore, angiotensin II receptor blockers (ARBs, i.e., losartan, valsartan and omelsartan) and angiotensin-converting enzyme inhibitors (ACEis, i.e., enalapril and linsinopril) are commonly prescribed to patients with oral cancers to treat hypertension and heart failure or prevent hypertensive nephropathy [3].