Our results of CA125 (82.4%) and HE4 (62.6%) sensitivities, however, were different from the above results, which may be caused by different disease-entry criteria—as CA125 and HE4 are also upregulated in many other diseases, including uterine fibroids, diverticulitis, endometriosis, liver cirrhosis, normal menstruation, and pregnancy26–28. Here, MUC16 is linked to uterine corpus leiomyoma.