P03 subcutaneous implanted in C57BL/6J mice treated with GY1-22 at 1 mg/kg, i.p. injection (n = 6 mice), showed a significant inhibition of in vivo tumor growth (Fig. 6, D–E, lower panels), which was comparable with P03 DNAJA1 knockout line. The gene discussed is H3P2; the disease is neoplasm.