To test this hypothesis and directly observe the dynamic changes of CRICs in response to P. aeruginosa infection, we performed P. aeruginosa (19660; ATCC) infection in the cornea of ko and wt control mice on the Csf1r-EGFP background and harvested them at 3 and 6 hpi for confocal microscopy. This evidence concerns the gene CSF1R and infection.