RT-PCR suggested that in PBMCs of BS patients had a higher mRNA expression: IFN-γ (11.24 ± 5.37, p < 0.001), CXCR3 (2.30 ± 0.58, p < 0.001), CXCL9 (2.37 ± 0.93, p < 0.01) and CXCL10 (6.02 ± 4.56, p < 0.001). This evidence concerns the gene CXCL9 and Bloom syndrome.