IGHE and food allergy: FAs can be further classified into (a) IgE-mediated; (b) non-IgE-mediated when the specific IgE to foods is not important and the cell compartment of the immune system is responsible of the food allergy; (c) mixed IgE-/cell-mediated when both IgE and immune cells are involved in the reaction [7,8,9,10].