Despite all of the limitations, empiric diets are still the most effective option in EoE, as allergy testing, such as measurements of specific IgE (in vivo via a skin prick test (SPT), or in vitro via serum analysis) and atopy patch tests, have been shown to be less effective than the empiric method to find the food trigger of EoE [59,75]. Here, IGHE is linked to eosinophilic esophagitis.