Other TAU interacting proteins with strong relevance for cancer are the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein CAPON [225], the probable ATP-dependent DEAD-Box RNA helicase DDX6 [226], the proto-oncogene tyrosine-protein kinase SRC [227], the tyrosine-protein kinase ABL1 [228], the dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A [229], the EWS RNA-binding protein 1 (EWSR1) [230] and the sirtuin family [231]. The gene discussed is EWSR1; the disease is cancer.