SRRM4 and central nervous system cancer: With respect to glioma, we identified a significant correlation (p < 0.0001) between low SRRM4 expression and poor survival in GBM and low-grade glioma across the Chinese Glioma Genome Atlas (CGGA), The Cancer Genome Atlas (TCGA) and Repository of Molecular Brain Neoplasia Data (Rembrandt) datasets (Figure S5b–d).