PRSS1 and neoplasm: Another interesting finding was the difference observed in TRY1 abundance in the advanced versus initial stage of M5-T1 tumor development, and the correlations observed with CHSP1, ECHA, FABP5, LYPA1, NCPR, and RTCB, among other proteins, which suggest they could represent important therapeutic targets for limiting the deleterious effect of invasive tumor cells on the liver.