While the underlying mechanistic pathways linking these serological factors to reduced cancer progression are not fully understood, there is accumulating evidence that IL‐6 release from skeletal muscle during exercise may play an important role, either directly or indirectly through the induction of anti‐inflammatory cytokines such as IL‐1 receptor antagonist (IL‐1ra) (Christensen et al., 2018; Petersen & Pedersen, 2005). The gene discussed is IL6; the disease is cancer.