Again, the analysis of the functional measurements showed no significant differences in heart rate (Fig. 3c) nor in the systolic parameters stroke volume (Fig. 3d), stroke work (Fig. 3e) or the contractility parameter PRSW (Fig. 3f) between TRPM4−/−(Bl/6N) and TRPM4+/+(Bl/6N) mice. The gene discussed is TRPM4; the disease is Stroke.