Second, because in vitro conditions do not fully mimic the tumor microenvironment and because MAIT cell ligands are highly unstable products,11 it would be important to evaluate how bacterial dose- and/or timing-dependent stimulations can affect MAIT cell activation as well as differential expression of pertinent genes, differences in the concentration of the metabolite produced by the bacteria, etc. Last, and mostly because of inadequate statistical power, this study indicates but falls short of fully demonstrating the effect of CD39+MAIT cells on the tumor microenvironment. The gene discussed is ENTPD1; the disease is neoplasm.