Previous works showed that suppression of GCS restored wild‐type p53 protein expression and its anticancer effects in NCI/ADR‐RES cancer cells carrying a TP53 deletion‐mutation,23, 45 and in SW48/TP53 cells heterozygous for a missense TP53 mutation (R273H/+) inserted with CRISPR/Cas9 gene editing.20, 22. The gene discussed is UGCG; the disease is cancer.